Fructose 1,6-bisphosphate (or fructose 1,6-diphosphate) is a chemical compound consisting of a phosphorylated fructose in C1 and C6, i.e. with a phosphate group on carbon 1 and carbon 6. It is an intermediate compound of glycolysis and of gluconeogenesis. By virtue of the slow intestinal absorption (facilitated diffusion) and the rapid hepatic metabolism, fructose does not increase blood sugar and insulinemia. Fructose is a very energetic food. It is also able to slow down the absorption rate of the other carbohydrates it is associated with, ensuring the long-term release of energy. Since the glycemic index of fructose is very low, especially when compared to that of common sugar (sucrose), its use in place of sugar appears to be useful in the prevention of type 2 diabetes and conditions such as overweight and obesity.